PEG–peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity

Differential Equation of Sensitivity Matrix for Final Velocity Constraint

the effects of error correction methods on pronunciation accuracy

هدف از انجام این تحقیق مشخص کردن موثرترین متد اصلاح خطا بر روی دقت آهنگ و تاکید تلفظ کلمه در زبان انگلیسی بود. این تحقیق با پیاده کردن چهار متد ارائه اصلاح خطا در چهار گروه، سه گروه آزمایشی و یک گروه تحت کنترل، انجام شد که گروه های فوق الذکر شامل دانشجویان سطح بالای متوسط کتاب اول passages بودند. گروه اول شامل 15، دوم 14، سوم 15 و آخرین 16 دانشجو بودند. دوره مربوطه به مدت 10 هفته ادامه یافت و د...

Influence of melanosome dynamics on melanoma drug sensitivity.

BACKGROUND Malignant melanomas are intrinsically resistant to many conventional treatments, such as radiation and chemotherapy, for reasons that are poorly understood. Here we propose and test a model that explains drug resistance or sensitivity in terms of melanosome dynamics. METHODS The growth and sensitivity to cisplatin of MNT-1 cells, which are melanotic and enriched with mature stage I...

Microenvironmental Effects on Enzyme Activity

One of the problems to be considered in evaluating the results of experiments involving fragmentation of cells and subcellular organelles and fractionation of the particles and supernatants obtained, is that enzymic activities measured by a standard assay at various stages of the procedure may not provide a true measure of the amount of a given enzyme which is present. In some cases the reason ...

Breast tumour initiating cell fate is regulated by microenvironmental cues from an extracellular matrix.

Cancer stem cells, also known as tumour-initiating cells (TICs), are identified as highly tumorigenic population within tumours and hypothesized to be main regulators in tumour growth, metastasis and relapse. Evidence also suggests that a tumour microenvironment plays a critical role in the development and progression of cancer, by constantly modulating cell-matrix interactions. Scientists have...